Ketoconazole shampoo-induced hair discoloration,

Hair discoloration caused by etretinate.

Ketoconazole shampoo: effect of long-term use in androgenic alopecia.

BACKGROUND The pathogenesis of androgenic alopecia is not fully understood. A microbial-driven inflammatory reaction abutting on the hair follicles might participate in the hair status anomaly. OBJECTIVE The aim of our study was to determine if ketoconazole (KCZ) which is active against the scalp microflora and shows some intrinsic anti-inflammatory activity might improve alopecia. METHOD T...

Determination of Ketoconazole in Shampoo by High Performance Liquid Chromatography

A high performance liquid chromatography isocratic procedure was developed for the assay of ketoconazole in shampoo. Two solutions, (A) monoisopropylamine-methanol (2:500, v/v) and (B) ammonium acetate-water (1:200, w/v) were prepared. The mobile phase is a mixture of A and B (7:3, v/v), with pH adjusted to 5.5 with acetic acid. The chromatographic system consists of a LiChrospher® 100 RP-8 col...

Highly efficient and compatible shampoo for use after hair transplant

BACKGROUND Sensitive or hyperreactive skin is a common condition defined by prickling, burning, pain, and pruritus. Although this skin problem was initially described on the face, the scalp is often affected. A sensitive scalp can react with irritation to harsh surfactants or other additives which are often present in shampoos. For this reason, we developed a new rinse-off hypertolerant shampoo...

Ketoconazole-induced fulminant hepatitis.

We report the cases of two adult patients in whom fulminant hepatitis developed after 17 and 103 days of ketoconazole administration. Histologic administration showed massive, predominantly centrilobular necrosis. Clinical manifestations of hypersensitivity and eosinophilia were absent in both patients, which suggests that ketoconazole hepatotoxicity is not mediated through an immunoallergic me...